Transsexual

Transsexual (also Transexual, occasionally Trans-Sexual) refers to an individual whose gender identity is in conflict with his or her sex at birth, and who often seeks Transition and/or Sex Reassignment Surgery to resolve the issue.

The double-S spelling is attributed to Harry Benjamin.

The term has explicit clinical definitions appearing in the Diagnostic and Statistical Manual of the American Psychiatric Association and other similar publications of various related organizations.